EUROPEAN RESPIRATORY UPDATE An update on paediatric asthma

نویسندگان

  • Gunilla Hedlin
  • Jon Konradsen
  • Andrew Bush
چکیده

Airway inflammation is one of the pathophysiological characteristics of asthma, which is mediated through infiltration of inflammatory cells, including mast cells, and eosinophilic and neutrophilic granulocytes in the airway wall. This cell infiltration subsequently leads to bronchial hyperresponsiveness (BHR) and, in the case of chronic inflammation, persistent changes of the airways, i.e. airway remodelling [3, 4].

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تاریخ انتشار 2012